Senior Lecturer

Dr. Herbert Itabangi

PROFILE

OVERVIEW

Herbert is a microbiologist, fungal immunologist and medical mycologist researching on cross-kingdom interactions and how human fungal pathogens survive and cause disease in the human host. Herbert joined Busitema University in September, 2020 as a senior lecturer in Microbiology and Immunology. He is an alumnus of the University of Birmingham (UoB) having completed his PhD under the supervision of Drs Elizabeth Ballou, Kirstin Voelz of UoB, Prof Gordon Brown, University of Exeter and Dr Jason King, Sheffield University, UK in 2019, which investigated how bacterial endosymbionts modulate innate immune responses during infection by Rhizopus Microsporus. Herbert has since returned to Uganda and now doing a postdoctoral fellowship funded by the European Developing Countries Clinical Trails partnership (EDCTP) based at Mbarara University of Science and Technology in collaboration with Busitema University, University of Birmingham (UK) and Sheffield University (UK) focusing on metabolic and molecular ecological evolution of opportunistic pulmonary fungal co-infections.

RESEARCH INTERESTS

Herbert is interested in understanding how fungi transition from environmental saprophytes to opportunistic pathogens focusing on how they interact and adapt to their environment, and the consequences these modifications have on disease progression. This includes, but is not limited to, understanding how fungi adapt to specific environmental signals (i.e. CO2, pH, temperature, pesticides, metabolites), but also how fungi interact with other opportunistic pathogens and members of the microbiome and how this influences pathogenicity and antifungal susceptibility responses. Herbert is also passionate about infection modeling using several infections including Mice, Zebrafish (Dario), Galleria mellonella, and Amoebae (Dictyostelium discoideum)

CURRENT PROJECTS

  1. Amoebae as an environmental in-vitro model to study Host-pathogen interactions in a resource-limited setting
  2. Elucidating the impact OF bacterial symbiosis on fungal virulence
  3. Phylogenetic diversity of antifungal drug resistance
  4. Antifungal Hetero-resistance among clinically isolated yeasts and molds

Contact

Department of Microbiology and Immunology,

Faculty of Health Sciences

Busitema University

P.O. Box 1460 Mbale, Uganda.

Mobile: +256-789434346 / 0775554564 / 0752381780

Email: hitabangi@fhs.busitema.ac.ug/ hitabangi@gmil.com

Skype: herbert.itabangi10

Twitter: @hitabangi

Orchid ID No: 0000-0003-3010-2537